New Hope for Patients with Werner Syndrome

Werner syndrome (WS) is a rare genetic disorder that causes premature aging and serious complications. In the first clinical trial of its kind, researchers from Japan with the company Niagen Bioscience, investigated the effects of nicotinamide riboside (NR), a vitamin B3 derivative, in patients with WS. NR supplementation significantly improved cardiovascular health, reduced skin ulcer area, and slowed kidney function decline—offering promising therapeutic potential for a disease that currently lacks effective treatment.